Professor Kamalinder K Singh
Kamalinder K Singh is Professor of Pharmaceutical Technology and Drug delivery. She is the Research and Knowledge Exchange Lead for the School. Professor Singh’s research is centred in the area of Nanomedicine and Advanced drug delivery. She has also provided leadership to more than 40 funded research projects as Principal Investigator. She was awarded and is managing several research projects funded by National Institute of Health (NIH), Academy of Medical Sciences (AMS), British Council, Foreign, Commonwealth and Development office (FCDO), and pharmaceutical industries.
Kamalinder, as School Research Knowledge Exchange Lead, provides leadership for developing new interdisciplinary research programs and cross functional collaborations and guides the strategic development and integration of research within the School with other Schools at UCLan and other Universities at National and International level. She is Co-Director of our Biomedical evidence based Transdisciplinary (BEST) Health Research Institute which links basic and translational investigations at the bench to the patient focused research. Kamalinder is a member of various committees at the University level, including the University Research Knowledge exchange and ethics Committee, the University REF Strategy Group, the Pro Vice Chancellor’s Research and Knowledge exchange Strategy Group. Kamalinder teaches on the Master of Pharmacy and various MSc postgraduate courses.
With more than 35 years of experience in academia and research, Kamalinder has developed extensive expertise in the field of Advanced drug delivery, Nanomedicine, and Drug targeting with focus on formulation design, development, and evaluation of different biocompatible nanoparticle-based platform technologies including protein, lipid and hybrid nanoparticles and exploiting them to deliver drugs and genes across various biological barriers.
With expertise from laboratory to scale up development, she actively collaborates with pharmaceutical industry and has contributed significantly to patents, innovation and intellectual property. She is principal inventor on 18 patents, which include US, UK, Europe, China, Chile and India filings. She has authored more than 100 original research, review publications and book chapters. She is the invited member of International Steering Board of Handbook of Pharmaceutical Excipients, Royal Pharmaceutical Society of Great Britain, and American Pharmaceutical Association (from 2005-present) and contributed over 60 monographs to various editions of the Handbook.
She has edited a reference book on Nanoparticle Therapeutics: Production technologies, Types of Nanoparticles and regulatory aspects, Elsevier (2022). She is also co-editor of the books, NanoNutraceuticals, part of series on ‘Emerging trends in Nanobiomedicine’ Taylor and Francis, CRC Press (2019) and Nanopharmaceuticals, Vol 2 Nanobiomedicine Series, Studium Press (2015).
Kamalinder has supervised over 30 PhD students and has examined a similar number. She has been an invited speaker at numerous national and international conferences around the globe. Prior to joining us in 2013, Kamalinder was Professor of Pharmaceutics at SNDT Women’s University (SNDTWU), Mumbai, India and also served as Dean of the Pharmacy college within SNDTWU.
- PhD Pharmaceutical Technology, SNDT Women’s University, Mumbai, 1993
- M Pharm (Pharmaceutics), Panjab University, Chandigarh, 1983
- B Pharm Panjab University, Chandigarh, 1981
- Best Pharmaceutical Scientist Award, National award by Association of Pharmaceutical Teachers of India, 2012
- State Teacher Award, by Government of Maharashtra in Engineering & Pharmacy teachers, 2011
- Pharmacy Teacher of Year Award for outstanding Pharmacy education - A national award given by Association of Pharmaceutical Teachers of India, 2008
- Outstanding Herbal Formulator Award at The International Seminar on Medicinal Plants and Herbal Product by Aromatic Plants Board, 2008
- Dr. R. L. Nicore Award in Pharmaceutics section for the Best article in IJPE, 2005
- Excellence in performance award by SNDT Women’s University, Mumbai, 2002
- First in Pharmaceutics, M Pharm, Panjab University, Chandigarh, 1983
- Lipid nanoparticles (LNPs) for gene delivery
- Cancer Nanomedicine
- Nanomedicine for infectious diseases
- Malaria Nanotherapeutics
- Surface active nanoparticles for fungal infections
- Brain drug delivery
- Skin drug delivery
- Nanocrystal technology for poorly water-soluble drugs
- Microparticles for taste masking
- Invited Member of International Steering of Handbook of Pharmaceutical Excipients, Royal Pharmaceutical Society of Great Britain, and American Pharmaceutical Association (2005-present)
- Topic Editor, Pharmaceutics (MPDI Publication)
- External Examiner, MSc Pharmaceutical and Biopharmaceutical formulations, Sunderland University
- Vice President and Scientific Chair, Controlled Release Society - Indian Chapter (2011-2013)
- Vice Chairperson AAPS Discussion Group (Western India) (2011-2013)
- Secretary and Co-Chair Scientific Committee, Controlled Release Society - Indian Chapter (2007-2011)
- Member British Society of Nanomedicine
- Member UK Ireland Chapter of Controlled release Society
- Member Controlled Release Society
- Member, Brain Tumour Northwest
- Visiting Fellow, UKIERI, University of Bradford (2012)
- Associate Fellow Higher Education Academy.
Prof Singh leads our Nanomedicine and innovative technologies research. Her group designs Quality by Design enabled tailored nanoparticles with predictable morphology, size, drug-loading and transport properties.
Her pioneering research has led to growing portfolio of robust, scalable, multifunctional hybrid nanoparticles, protein nanoparticles and lipid-nanostructure platforms for enabling drugs to cross air-lung pulmonary barrier, blood-brain-barrier, gastrointestinal and cutaneous barriers. Her group utilises range of scalable technologies including microfluidic technology, high pressure homogenisation, nano-milling for development of nanoparticles, and surface functionalisation to customise nano-bio-interactions; the development span the following areas: pre-formulation, formulation development, physicochemical assessment, stability assessment, in vitro cell culture and transport mechanisms, nanomaterial cell interactions, pharmacokinetics, and bio-distribution and in vitro-in vivo correlation.
She has developed vectors for the efficient delivery and targeting of anti-bacterial, anti-fungal drugs, and selective targeting of antimalarial drugs to malaria parasitized red blood cells (RBCs) showing complete discrimination from normal RBCs. Her work is interdisciplinary and underpinned by collaborations with physiologists, pharmacologists, biologists, and clinicians. Her work on cancer targeting includes development of nanotherapeutic systems for brain, breast, colon, and ovarian cancer.
She has made significant contribution in the development of lipid nanostructures for deeper layer skin targeting of difficult to load drugs for chronic dermatological conditions (atopic dermatitis, psoriasis). She also has interest in applying nanotechnologies to phyto-molecules and traditional herbal drugs to develop nanophytomedicines. Her ongoing research is on nucleic acid delivery using lipid nanoparticles and their systematic development to define product and process parameters to facilitate particle stability, transfection efficiency and permeation across physiological barriers.
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- Biomedical Evidence based Transdisciplinary (BEST) Health Research Institute
- Nanomedicine
- Neuro-oncology
- Brain Tumour Northwest
- RNA Interference for glioblastoma therapy using lipid nanoparticles
- siRNA delivery using lipid nanoparticles for modulating inflammation in fungal lung infections
- miRNA loaded lipid nanoparticles for targeting osteoporosis
- Bio-inspired nanoparticles for targeting malaria infected red blood cells
- Nanostructured lipid carriers for fungal skin infections
- Nanostructured lipid carriers for chronic wound infections
- Polyunsaturated fatty acids for targeting and co-delivery with anticancer agents in glioblastoma
- Lipid nanostructured carriers for ovarian cancer
- Microparticles for transforming oils to powder
- Foreign, Commonwealth and Development office (FCDO), £39686, 2023-2024, RNA Interference for Osteoporosis therapy using lipid nanoparticles
- Foreign, Commonwealth and Development office (FCDO), £37686, 2023-2024, Nanostructured Lipid Vesicular Systems for effective treatment of fungal skin infections
- UCLan DTC training Centre PhD studentship, £84717, 2022-2026, RNA Interference for Glioblastoma therapy using lipid nanoparticles
- National Institute of Health, $485,000, 2021-2023, Novel nanoparticles function as chemo- and adjunctive-therapy against experimental cerebral malaria
- Academy of Medical Sciences, Newton International Fellowship, £107,000, 2021-2023, Long-acting surface-engineered nanocarrier system for codelivery of temozolomide with polyunsaturated fatty acid for the improved treatment of glioblastoma multiforme
- British Council £10,000, 2022-2023, Functionalised Nanostructured Lipid Carriers to Deliver miRNA-214a for Targeting Osteoporosis In-Vivo
- Department of international development, £42,100, 2021-2022, Nanocarrier mediated Topical treatment for Diabetic Foot Ulcer
- UCLan Research to Market, £25,000, 2020, Transforming Oils/Oily bioactives into free-flowing solid microparticles to mask their unpleasant taste/odour to facilitate oral administration and improve patient compliance’ Scale-up studies were performed in collaboration with Centre of Pharmaceutical Innovation, UK
- Industry funding Wockhardt UK Ltd., £61,278, 2019-2021, Breaching Complex Biological Barriers using Innovative Nanostructures for Improved Drug Therapeutics
- Department of international development, £ 42,100, 2019-2021, Fighting biofilms and antimicrobial resistance with functionalised Next generation Nano-Antibiotics
- Department of international development, £ 43,100, 2019 -2021, Lipid Nanocarrier mediated ointment of white curcumin as novel therapeutics for atopic dermatitis
- LIFE (The Lancashire Research Institute for Global Health & Wellbeing), £14907, 2019-2020, Writing Group-Nanomedicine for targeted delivery
- Department of international development, £32,100, 2017-2018, Inhalable antifungal drug delivery for the efficient treatment of pulmonary aspergillosis
- UCLan Innovation team, 2016-2017; £37,500 Transforming Oils/Oily bioactives into free-flowing solid microparticles to mask their unpleasant taste/odour to facilitate oral administration and improve patient compliance
- Industry funding Wockhardt UK Ltd., £98,500, 2014-2017, Design and Evaluation of Targeted Nanoparticulate Drug Delivery System for the Treatment of Brain Cancer
- Invited speaker, International Pharmaco-parasitology Conference on World Malaria Day, Postgraduate institute of medical education and research (PGIMER), Chandigarh, India, April 2023
- Invited speaker, Conference by British Society of Nanomedicine, hosted by Swansea University, July 2022
- Invited speaker, NextGen Therapeutics & Diagnostics: Concept to Commercialization, NIPER, Hyderabad, April 2022
- Keynote speaker, International conference on Nanomedicine: Biomolecules for human health small molecules-big opportunities, University of Delhi, September 2021
- Invited speaker, Formulation and Delivery Conference, Oxford Global conference, London, September 2021
- Plenary speaker, ‘ICONICA Global Conference on NextGen Paradigms in Healthcare’, Chandigarh, February 2020
- International Advisory Board, ‘ICONICA Global Conference on NextGen Paradigms in Healthcare’, Chandigarh, February 2020
- Distinguished Collaborator, Connecting Minds on patients with Dysphagia, organised LIFE, UCLan, May 2019
- Invited Speaker, 5th International Global Health and Wellbeing research with real impact conference, UCLan, 2019
- Invited speaker, 5th Annual Formulation & Drug Delivery Congress, Oxford Global conference, London, April 2019
- Invited speaker, 6th World Congress on Nanomedical Sciences, University of New Delhi, January 2019
- Invited speaker, SPER 7th Annual International Conference & Exhibition, Chennai, India, February 2018
- Invited speaker, Ajman University, Dubai, UAE, 2018
- Invited speaker, RAK University, UAE, Feb 2018
- Invited speaker, BITS Pillani, Dubai Campus, Dubai, Feb 2018
- Invited speaker, 5th International Conference on Nanotechnology in Medicine, British Nanomedicine Society, Manchester, June 2018
- Keynote speaker, Faculty development Programme, Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, Mumbai, 2018
- Invited speaker, 2nd International workshop on Nanomaterials in Health/Medicine, UCLan, UK January 2018
- Advisory Panel, NanoSciTech 2017, Panjab University, Chandigarh, India, November 2017
- Plenary Lecture, NanoSciTech 2017, Panjab University, Chandigarh, India, November 2017
- Erasmus plus mobility, University of Coimbra, Portugal, May 2017
- Invited speaker, 2nd Formulation and Drug delivery Conference, Oxford Global. London, May 2016
- Invited speaker, International Conference on Translational Nanomedicne (T-Nano 2014), Ahmedabad, India, December 2014
- Invited speaker, 5th Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalent in Asian Countries, Tokyo, Japan, September 2014
- Invited speaker, Beating Malaria, London, July 2014
- Plenary lecture, ‘NanoScitech 2014’ Chandigarh February 2014
- Symposium Chair, 13th International Symposium on Advances in Technology and Business Potential of New Drug Delivery Systems, Controlled Release Society- Indian Chapter, 2013
- Invited speaker 4th Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalent in Asian Countries, Tokyo, Japan, October 2012
- Invited Speaker, 8th Nano TR, Ankara, Turkey, June 2012
- Symposium Chair, 12th International Symposium on Advances in Technology and Business Potential of New Drug Delivery Systems,” organized by Controlled Release Society- Indian Chapter, February 2012
- Symposium Chair, 11th International Symposium on Advances in Technology and Business Potential of New Drug Delivery Systems, organized by Controlled Release Society - Indian Chapter, February 2011
- Invited speaker, 8th Annual Congress of IDDST, Beijing China, 25-28th October 2010
- EHRLICH II, 2nd World Conference on Magic Bullets, Nurnberg, Germany, October 2008
- Invited Speaker, First Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases at Tokyo, Japan, 6-7th November 2007
- Invited speaker, 13th International Pharmaceutical Technology Symposium on ‘Opportunities and Challenges
Telephone:+441772895843
Email: Email:Professor Kamalinder K Singh
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